The effects of calyculin A upon calcium-, guanine nucleotides- and phorbol 12-myristate 13-acetate-stimulated ACTH secretion from AtT-20 cells
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منابع مشابه
Effects of phorbol-12-myristate-13-acetate on the phenotypic program of cultured chondroblasts and fibroblasts.
Phorbol-12-myristate-13-acetate (PMA) has a prompt, differential, and partially reversible effect on cultured chick chondroblasts. Within 36 hr PMA transforms sessile, polygonal, epithelioid chondroblasts into motile, multilayered, fibroblastic cells. In PMA chick chondroblasts rapidly cease to synthesize two of their terminal luxury molecules, the type IV sulfated proteoglycan that characteriz...
متن کاملProgram of Cultured Chondroblasts and Fibroblasts Effects of Phorbol-12-myristate-13-acetate on the Phenotypic
Phorbol-12-myristate-13-acetate (PMA) has a prompt, differential, and partially reversible effect on cultured chick Chondroblasts. Within 36 hr PMA transforms sessile, polygonal, epithelioid Chondroblasts into motile, multilayered, fibroblastic cells. In PMA chick Chondroblasts rap idly cease to synthesize two of their terminal luxury molecules, the type IV sulfated proteoglycan that charac ter...
متن کاملEffects of phorbol 12-myristate 13-acetate on the differentiation program of embryonic chick skeletal myoblasts.
The effects of phorbol 12-myristate 13-acetate (PMA) on three aspects of myogenesis have been analyzed: (a) fusion of mononucleated myogenic cells to form myotubes; (b) synthesis and accumulation of two muscle-specific proteins; and (c) DNA synthesis. Using autoradiography combined with immunofluorescent localization of muscle-specific light meromyosin and the muscle-specific intermediate filam...
متن کاملEffects of Phorbol 12-Myristate 13-Acetate on the Differentiation Program of Embryonic Chick Skeletal Myoblasts1
The effects of phorbol 12-myristate 13-acetate (PMA) on three aspects of myogenesis have been analyzed: (a) fusion of mononucleated myogenic cells to form myotubes; (b) synthesis and accumulation of two muscle-specific proteins; and (c) DNA syn thesis. Using autoradiography combined with immunofluorescent localization of muscle-specific light meromyosin and the musclespecific intermediate filam...
متن کاملNanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment
The adhesion and traction behavior of leukemia cells in their microenvironment is directly linked to their migration, which is a prime issue affecting the release of cancer cells from the bone marrow and hence metastasis. In assessing the effectiveness of phorbol 12-myristate 13-acetate (PMA) treatment, the conventional batch-cell transwell-migration assay may not indicate the intrinsic effect ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1995
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1995.tb14941.x